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Naloxone-N-oxide (4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-oxido-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-3-ium-7-one. 112242-14-5.
May 14, 2010 Pharmacology: Vardenafil is a selective PDE5 inhibitor. Metabolism: Vardenafil was extensively metabolized via N-deethylation, oxidation,
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Alternate CAS#: Molecular Formula: C 23 H 32 N 6 O 5 S. Molecular Weight: 504.61 Vardenafil (VRD) and sildenafil (SLD) are phosphodiesterase-5 (PDE5) inhibitors available by prescription in the U.S. for the treatment of erectile dysfunction. The two compounds are structurally very similar, with differences only in the position of a nitrogen in the fused heterocyclic rings and the alkyl group (ethyl for VRD, methyl for SLD) attached to the piperazine ring ( Fig.␣1 ). Naloxone N-Oxide. Naloxone-N-oxide (4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-oxido-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-3-ium-7-one.
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Naloxone N-Oxide. Naloxone-N-oxide (4R,4aS,7aR,12bS)-4a,9-dihydroxy-3-oxido-3-prop-2-enyl-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-3-ium-7-one.
Mol.Wt. : 504.61. Inv. Status: In Stock.
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